The Department of Natural Science notebooks are course notebooks maintained by faculty in the Michigan State Normal College Department of Natural Science. Notebooks include such information as course rosters, grades, and curriculum. Also included in the collection is a series of correspondence notebooks.

The Department of Natural Science notebooks have been arranged into series by faculty member/author. Notebooks within in each series have been arranged chronologically. In some instances, multiple courses taught by multiple faculty are included in one bound notebook; in those cases the notebooks are listed under all relevant faculty, and include all relevant years.